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KMID : 0361020190620110657
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Korean Journal of Otolaryngology - Head and Neck Surgery
2019 Volume.62 No. 11 p.657 ~ p.662
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Two Cases of Localized Myeloperoxidase-Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Manifested with Intractable Otitis Media
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Lee Eun-Kyu
Chung Won-Ho
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Abstract
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Localized form of myeloperoxidase-antineutrophil cytoplasmic antibody-associated vasculitis(MPO-AAV) in the ear is a rare disease. It manifests as a sudden otalgia with hearing loss accompaniedby dizziness and facial nerve palsy. Early diagnosis and treatment with immunosuppressiveagents are important to prevent the irreversible progression of sensorineural hearingloss. However, it is hard to diagnose AAV because it can be confused with other commonotologic disease, such as acute otitis media or middle ear effusion with labyrinthitis. Here, we report two cases of localized form of MPO-AAV manifesting otologic symptomsthat have been properly diagnosed and treated with steroid and immunosuppressant.
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KEYWORD
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Antibodies, Antineutrophil cytoplasmic, Otitis media, Myeloperoxidases
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